Below is a comprehensive list of publications from C2B2, accompanied by their relevant analytics.
Google Scholar: Doralyn S. Dalisay
National Library of Medicine: Doralyn S. Dalisay
54. Tenebro, C.P., Marcial, N.B.J.M., Salcepuedes, J.J., Torrecampo, J.C., Hernandez, R.D., Francisco, J.A.P., Infante, K.M.G., Belardo, V.J., Paderes, M.C., Alvero, R.G.Y., Saludes, J.P., Dalisay, D.S., Visualization of renal rotenone accumulation after oral administration and in situ detection of kidney injury biomarkers via MALDI mass spectrometry imaging. Frontiers Molecular Biosciences. 2024, 11. https://doi.org/10.3389/fmolb.2024.1366278
53. Dalisay, D.S.; Tenebro, C.P.; Sabido, E.M.; Suarez, A.F.L.; Paderog, M.J.V.; Reyes-Salarda, R.; Saludes, J.P. Marine-Derived Anticancer Agents Targeting Apoptotic Pathways: Exploring the Depths for Novel Cancer Therapies. Mar. Drugs 2024, 22, 114. https://doi.org/10.3390/md22030114
53. Dalisay, D.S.; Tenebro, C.P.; Sabido, E.M.; Suarez, A.F.L.; Paderog, M.J.V.; Reyes-Salarda, R.; Saludes, J.P. Marine-Derived Anticancer Agents Targeting Apoptotic Pathways: Exploring the Depths for Novel Cancer Therapies. Mar. Drugs 2024, 22, 114. https://doi.org/10.3390/md22030114
52. Abordo, A.M.S.; Carascal, M.B.; Remenyi, R.; Dalisay, D.S.; Saludes, J.P. Clinically Isolated β-Lactam-Resistant Gram-Negative Bacilli in a Philippine Tertiary Care Hospital Harbor Multi-Class β-Lactamase Genes. Pathogens 2023, 12, 1019.
https://doi.org/10.3390/pathogens12081019
https://doi.org/10.3390/pathogens12081019
51. Suarez, A.F.L.; Juanillo, A.A.B.; Sison, D.C.D.; Orajay, J.I.; Javier, M.B.B.; Baladjay, D.M.S.; Yang, Y.L.; Saludes, J.P.; Dalisay, D.S. In situ spatiotemporal mapping of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) inhibitor in pineapple (Ananas comosus) fruit tissue by MALDI mass spectrometry imaging. Frontiers in Natural Products 2023, 2, 5.
https://doi.org/10.3389/fntpr.2023.1160541
https://doi.org/10.3389/fntpr.2023.1160541
50. Tenebro, C.P.; Trono, D.J.V.L.; Balida, L.A.P.; Bayog, L.K.A.; Bruna, J.R.;, Sabido, E.M.; Caspe, D.P.C.; de Los Santos, E.L.C.; Saludes, J.P.; Dalisay, D.S. Synergy between Genome Mining, Metabolomics, and Bioinformatics Uncovers Antibacterial Chlorinated Carbazole Alkaloids and Their Biosynthetic Gene Cluster from Streptomyces tubbatahanensis sp. nov., a Novel Actinomycete Isolated from Sulu Sea, Philippines. Microbiol Spectr. 2023 11(2):e0366122.
https://doi.org/10.1128/spectrum.03661-22
https://doi.org/10.1128/spectrum.03661-22
49. Zulkifli, M.F.; Radzi, M.N.F.M.; Saludes, J.P.; Dalisay, D.S.; Ismail, W.I.W. Potential of natural honey in controlling obesity and its related complications. Journal of Evidence-Based Integrative Medicine 2022, 27, 2515690X221103304.
https://doi.org/10.1177/2515690X221103
https://doi.org/10.1177/2515690X221103
48. Williams, D.E.; Morgan, K.D.; Dalisay, D.S.; Matainaho, T.; Perrachon, E.; Viller, N.; Delcroix, M.; Gauchot, J.; Niikura, H.; Patrick, B.O.; et al. Natural Products Produced in Culture by Biosynthetically Talented Salinispora arenicola Strains Isolated from Northeastern and South Pacific Marine Sediments. Molecules 2022, 27, 3569.
https://doi.org/10.3390/molecules27113569
https://doi.org/10.3390/molecules27113569
47. Dumancas, G.G.; Setijadi, C.; Dufour, B.; Aglobo, J.; Carisma, M.S.; Bello, G.A.; Dalisay, D.S.; Saludes, J.P. Comparison of Genetic and Non-genetic and Algorithm Partia Least Squares for Sugar Qunatification in the Philippine Honeys. Analytical Letters 2022 55 (12), 1901-1918.
https://doi.org/10.1080/00032719.2022.2033985
https://doi.org/10.1080/00032719.2022.2033985
46. Balida, L.A.P.; Regalado, J.T.A.; Teodosio, J.J.R.; Dizon, K.A.H.; Sun, Z.; Zhan, Z.Q.; Blancaflor, J.M.D.; Sollesta, J.V.N.; Villorente, Z.M.; Saludes, J.P.; Dalisay, D.S. Antibiotic Isoflavonoids, Anthraquinones, and Pterocarpanoids from Pigeon Pea (Cajanus cajan L.) Seeds against Multidrug-Resistant Staphylococcus aureus. Metabolites 2022, 12, 279.
https://doi.org/10.3390/metabo12040279
https://doi.org/10.3390/metabo12040279
44. Villanueva, N. S. P.; Vicera, C. V. B.; Leonida, S. F. L.; Paderog, M. J.; Sabido, E. M.; Saludes, J. P; Dalisay, D. S. Barringtonia asiatica Seed Extract Induces G1 Cell Cycle Arrest in Saccharomyces cerevisiae and Exhibits Cytotoxicity in A2780 Human Ovarian Cancer Cells, Journal of Pharmaceutical Research International, 2021, 33(53A), 372-387.
https://doi.org/10.9734/jpri/2021/v33i53A33672
https://doi.org/10.9734/jpri/2021/v33i53A33672
43. Makarieva, T.N.; Ivanchina, N.V.; Dmitrenok, P.S.; Guzii, A.G.; Stonik, V.A.; Dalisay, D.S.; Molinski, T.F. Oceanalin B, a Hybrid α,ω-Bifunctionalized Sphingoid Tetrahydroisoquinoline β-Glycoside from the Marine Sponge Oceanapia sp. Marine Drugs 2021, 19, 635. https://doi.org/10.3390/md19110635
42. Tenebro, C.P.; Trono, D.J.V.L.; Vicera, C.V.B.; Sabido, E.M.; Ysulat, J.A.Y.; Macaspac, A.J.M.; Tampus, K.A.; Fabrigar, T.A.P.; Saludes, J.P.S.; Dalisay, D.S. Multiple strain analysis of Streptomyces species from Philippine marine sediments reveals intraspecies heterogeneity in antibiotic activities. Scientific Reports 2021, 11, 17544.
https://doi.org/10.1038/s41598-021-96886-4
https://doi.org/10.1038/s41598-021-96886-4
41. Sabido, E.M.; Tenebro, C.P.; Trono, D.J.V.L.; Vicera, C.V.B.; Leonida, S.F.L.; Maybay, J.J.W.B.; Reyes-Salarda, R.; Amago, D.S.; Aguadera, A.M.V.; Octaviano, M.C.; Saludes, J.P.; Dalisay, D.S. Insights into the Variation in Bioactivities of Closely Related Streptomyces Strains from Marine Sediments of the Visayan Sea against ESKAPE and Ovarian Cancer.
Marine Drugs 2021, 19, 441.
https://doi.org/10.3390/md19080441
Marine Drugs 2021, 19, 441.
https://doi.org/10.3390/md19080441
40. Suarez, A.F.L.; Tirador, A.D.G.; Villorente, Z.M.; Bagarinao, C.F.; Sollesta, J.V.N.; Dumancas, G.G.; Sun, Z.; Zhan, Z.Q.; Saludes, J.P.; Dalisay, D.S. The Isorhamnetin-Containing Fraction of Philippine Honey Produced by the Stingless Bee Tetragonula biroi Is an Antibiotic against Multidrug-Resistant Staphylococcus aureus. Molecules 2021, 26, 1688.
https://doi.org/10.3390/molecules26061688
https://doi.org/10.3390/molecules26061688
39. Dalisay, D.S., Rogers,E.W., Molinski, T.F. Oceanapiside, a Marine Natural Product, Targets the Sphingolipid Pathway of Fluconazole-Resistant Candida glabrata. Marine Drugs 2021, 19, 126.
https://doi.org/10.3390/md19030126
https://doi.org/10.3390/md19030126
38. Sabido, E.M.; Tenebro, C.P.; Suarez, A.F.L.; Ong, S.D.C.; Trono, D.J.V.L.; Amago, D.S.; Evangelista J.E. Jr.; Reynoso, A.M.Q.; Villalobos, I.G.M.; Alit, L.D.D.; Surigao, C.F.; Villanueva, C.A.; Saludes, J.P.; Dalisay, D.S. Marine Sediment-Derived Streptomyces Strain Produces Angucycline Antibiotics against Multidrug-Resistant Staphylococcus aureus Harboring SCCmec Type 1 Gene. Journal in Marine Science and Engineering. 2020, 8 (10), 734;
https://doi.org/10.3390/jmse8100734
https://doi.org/10.3390/jmse8100734
37. Paderog, M.J.V.; Suarez, A.F.L.; Sabido, E.M.; Low, Z.J.; Saludes, J.P.; Dalisay, D.S. Anthracycline Shunt Metabolites From Philippine Marine Sediment-Derived Streptomyces Destroy Cell Membrane Integrity of Multidrug-Resistant Staphylococcus aureus. Frontiers in Microbiology 2020, 11, 743.
DOI:10.3389/fmicb.2020.00743
DOI:10.3389/fmicb.2020.00743
36. Williams, D.E., Dalisay, D.S., Chen, J., Polishchuk, E.A., Patrick, B.O., Narula, G., Ko, M., Av-Gay, Y., Li, H., Magarvey, N., Andersen, R.J. Aminorifamycins and sporalactams produced in culture by a Micromonospora sp. isolated from a Northeastern-Pacific marine sediment are potent antibiotics. Organic Letters. 2017, 19, (4), 766–769
DOI:10.1021/acs.orglett.6b03619
DOI:10.1021/acs.orglett.6b03619
35. Jamison, M.; Dalisay, D.S.; Molinski, T. F. Peroxide Natural Products from Plakortis zyggompha and the Sponge Association Plakortis halichondrioides-Xestospongia deweerdtae. Antifungal Activity Against Cryptococcus gattii. Journal of Natural Products. 2016, 79 (3), 555–563.
DOI: 10.1021/acs.jnatprod.5b00951
DOI: 10.1021/acs.jnatprod.5b00951
34. Williams, D.; Izard, F.; Arnould, S.; Dalisay, D.S.; Tantapakul, C.; Maneerat, W.; Matainaho, T.; Julien, E.; Andersen, R. J. Structures of Nahuoic Acids B to E Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment and Evidence for the Inhibition of the Histone Methyl Transferase SETD8 in Human Cancer Cells by Nahuoic Acid A. Journal of Organic Chemistry. 2016, 81 (4), 1324–133.
DOI 10.1021/acs.joc.5b02569
DOI 10.1021/acs.joc.5b02569
33. Dalisay, D.S.; Kim, K.W.; Lee, C.; Yang, H.; Rübel, O.; Bowen, B.P.; Davin, L.B.; Lewis, N.G. Dirigent-Protein-Mediated Lignan and Cyanogenic Glucoside Formation in Flax Seed: Integrated Omics and MALDI Mass Spectrometry Imaging.
Journal of Natural Products, 2015, 26, 78(6), 1231-42.
DOI: 10.1021/acs.jnatprod.5b00023
Journal of Natural Products, 2015, 26, 78(6), 1231-42.
DOI: 10.1021/acs.jnatprod.5b00023
32. Monreal I.A., Liu, Q., Tyson, K., Bland, T., Dalisay. D.S., Adams, E.V., Wayman, G.A., Aguilar, H.C. and Saludes, J.P. Branched dimerization of Tat peptide improves permeability to HeLa and hippocampal neuronal cells. Chemical Communications (Cambridge). 2015, 51, 5463-5466.
DOI: 10.1039/C5CC00882D.
DOI: 10.1039/C5CC00882D.
31. Seneviratne, H.R., Dalisay, D.S., Kim, K.W., Moinuddin, S.G.A., Yang, H., Hartshorn, C.M., Davin, L.B. and Lewis, N.G. Non-host disease resistance response in pea (Pisium sativum) pods: Biochemical function of DRR-206 and phytoalexin pathway localization. Phytochemistry, 2015, 113, 140–148.
http://dx.doi.org/10.1016/j.phytochem.2014.10.013.
http://dx.doi.org/10.1016/j.phytochem.2014.10.013.
30. Marques, J.V., Dalisay, D.S., Yang, H., Lee, C., Davin, L.B. and Lewis NG. A multi-omics strategy resolves the elusive nature of alkaloids in Podophyllum species. Molecular BioSystems. 2014, 10, 2838-2849.
DOI: 10.1039/c4mb00403e.
DOI: 10.1039/c4mb00403e.
29. Ratnaweera, P., Williams, D.E., de Silva, E. D., Wijesundera, R., Dalisay, D.S and Andersen, R.J. Helvolic acid, an antibacterial nortriterpenoid from a fungal endophyte, Xylaria sp. of orchid Anoectochilus setaceus endemic to Sri Lanka. Mycology 2014, 5, 23-28.
DOI: 10.1080/21501203.2014.892905
DOI: 10.1080/21501203.2014.892905
28. Costa, M.A., Marques, J.V., Dalisay, D.S., Herman, B., Bedgar, D.L., Davin, L.B. and Lewis N.G. Transgenic hybrid poplar for sustainable and scalable production of the commodity/specialty chemical, 2-phenylethanol. PLoS One, 2013 Dec 26;8(12):e83169.
DOI: 10.1371/journal.pone.0083169.
DOI: 10.1371/journal.pone.0083169.
27. Dalisay, D.S., Williams, D.E., Wang, X. L., Centko, R., Chen, J., and Andersen, R. J. Marine sediment-derived Streptomyces bacteria from British Columbia, Canada are a promising microbiota resource for the discovery of antimicrobial natural products. PLoS One, 2013 8:e77078
DOI: 10.1371/journal.pone.0077078
DOI: 10.1371/journal.pone.0077078
26. Du, Y.L., Dalisay, D.S., Andersen, R. J., and Ryan, K. S. N-Carbamoylation of 2,4-diaminobutyrate reroutes the outcome in padanamide biosynthesis. Chemistry and Biology, 2013, 20, 1002-11.
DOI:10.1016/j.chembiol.2013.06.013
DOI:10.1016/j.chembiol.2013.06.013
25. Williams, D.E., Dalisay, D.S., Li, F., Amphlett, J., Maneerat, W., et al. Nahuoic acid A produced by a Streptomyces sp. isolated from a marine sediment is a selective SAM- competitive inhibitor of the histone methyltransferase SETD8. Organic Letters, 2012, 15, 414-417.
DOI: 10.1021/ol303416k.
DOI: 10.1021/ol303416k.
24. Noro, J.C., Kalaitzis, J.A., Williams, D.E., Dalisay, D.S., Andersen, R.J., and Neilan, B.A. Tyrocidine a from a haliclona sponge derived Vibrio sp. Planta Medica, 2012, 78, 1161.
DOI: 10.1055/s-0032-1320761.
DOI: 10.1055/s-0032-1320761.
23. Williams, D.E., Dalisay, D.S., Patrick, B.O., Matainaho, T., Andrusiak, K., Deshpande, R., Myers, C.L., Piotrowski, J.S., Boone, C., Yoshida, M., Andersen, R. J. Padanamides A and B, highly modified linear tetrapeptides produced in culture by a Streptomyces sp. isolated from a marine sediment. Organic Letters, 2011, 13, 3936-9.
DOI: 10.1021/ol2014494.
DOI: 10.1021/ol2014494.
22. Dalisay, D.S., Saludes, J.P., Molinski, T.F. Ptilomycalin A inhibits laccase and melanization in Cryptococcus neoformans. Bioorganic and Medicinal Chemistry. 2011,19, 6654-6657.
DOI: 10.1016/j.bmc.2011.05.041.
DOI: 10.1016/j.bmc.2011.05.041.
21. Pimenta, E. F., Vita-Marques, A. M., Tininis, A., Seleghim, M. H., Sette, L. D., Veloso, K., Ferreira, A. G., Williams, D. E., Patrick, B. O., Dalisay, D. S., Andersen, R. J., Berlinck, R. G. Use of experimental design for the optimization of the production of new secondary metabolites by two Penicillium species. Journal of Natural Products. 2010, 73, 11:1821- 32.
DOI: 10.1021/np100470h
DOI: 10.1021/np100470h
20. Dalisay, D. S., Quach T, Molinski T. F. Liposomal circular dichroism. Assignment of remote stereocenters in plakinic acids K and L from a Plakortis-Xestospongia sponge association. Organic Letters, 2010, 12, 7:1524-7.
DOI: 10.1021/ol100249v.
DOI: 10.1021/ol100249v.
19. Rogers, E. W., Dalisay, D. S., Molinski, T F. Zwittermicin A: synthesis of analogs and structure- activity studies. Bioorganic and Medicinal Chemistry Letters, 2010, 20, 7:2183- 5.
DOI: 10.1016/j.bmcl.2010.02.032.
DOI: 10.1016/j.bmcl.2010.02.032.
18. Dalisay, D. S., Molinski, T. F. Structure elucidation at the nanomole scale. 3. Phorbasides G from Phorbas sp. Journal of Natural Products, 2010, 73, 4:679-82.
DOI: 10.1021/np1000297
DOI: 10.1021/np1000297
17. Skepper, C. K., Dalisay, D. S., Molinski, T. F. Synthesis and chain-dependent antifungal activity of long-chain 2H-azirine-carboxylate esters related to dysidazirine. Bioorganic and Medicinal Chemistry Letters, 2010, 20, 6:2029-32.
DOI: 10.1016/j.bmcl.2010.01.068.
DOI: 10.1016/j.bmcl.2010.01.068.
16. Makarieva, T. N., Zakharenko, A. M., Dmitrenok, P. S., Guzii, A. G., Denisenko, V. A., Savina, A. S., Dalisay, D. S., Molinski,T. F., Stonik, V. A. Isorhizochalin: a minor unprecedented bipolar sphingolipid of stereodivergent biogenesis from the Rhizochalina incrustata. Lipids, 2009, 44, 12:1155-62.
DOI: 10.1007/s11745-009-3360-0.
DOI: 10.1007/s11745-009-3360-0.
15. Smith, A. B. III, Liu Z, Hogan A. M., Dalisay, D. S., Molinski, T. F. Hemi-phorboxazole A: structure confirmation, analogue design and biological evaluation. Organic Letters, 2009, 11, 16:3766-9.
DOI: 10.1021/ol9014317.
DOI: 10.1021/ol9014317.
14. Dalisay, D. S., Morinaka, B. I., Skepper, C. K., Molinski, T. F. A tetrachloro polyketide hexahydro-1H-isoindolone, muironolide A, from the marine sponge Phorbas sp. natural products at the nanomole scale. Journal of the American Chemical Society, 2009, 131, 22:7552-3.
DOI: 10.1021/ja9024929
DOI: 10.1021/ja9024929
13. Dalisay, D. S., Quach, T, Nicholas, G. N., Molinski, T. F. Amplification of the Cotton effect of a single chromophore through liposomal ordering-stereochemical assignment of plakinic acids I and J. Angewandte Chemie International Edition Engl. 2009, 48, 24:4367-71.
DOI: 10.1002/anie.200900888.
DOI: 10.1002/anie.200900888.
12. Mulder, R. J., Shafer, C. M., Dalisay, D. S., Molinski, T. F. Synthesis and structure- activity relationships of bengazole A analogs. Bioorganic and Medicinal Chemistry Letters, 2009, 19,11:2928-30.
DOI: 10.1016/j.bmcl.2009.04.069.
DOI: 10.1016/j.bmcl.2009.04.069.
11. Dalisay, D. S., Molinski, T. F. Structure elucidation at the nanomole-scale. Organic Letters, 2009, 11, 1967-70.
DOI: 10.1021/ol9004189.
DOI: 10.1021/ol9004189.
10. Dalisay, D. S., Molinski, T. F. NMR quantitation of natural products at the nano-mole scale. Journal of Natural Products. 2009, 72, 739-44.
DOI: 10.1021/np900009b
DOI: 10.1021/np900009b
9. Dalisay, D. S., Rogers, E. W., Edison, A. S., Molinski, T. F. Structure elucidation at the nanomole-scale. 1. Trisoxazole macrolides and thiazole-containing cyclic peptides from the nudibranch Hexabranchus sanguineus. Journal of Natural Products, 2009, 72, 732-38.
DOI: 10.1021/np8007649.
DOI: 10.1021/np8007649.
8. Dalisay, D. S., Tsukamoto, S. Molinski, T. F. Absolute Configuration of the bifunctionalized sphingolipid leucettamol A from Leucetta microrhaphis by deconvoluted exciton coupled CD. Journal of Natural Products, 2009, 72, 353-359.
DOI: 10.1021/np800549n.
DOI: 10.1021/np800549n.
7. Molinski, T. F., Dalisay, D. S., Lievens, S. L., Saludes, J. P. Drug development from marine natural products. Nature Reviews Drug Discovery. 2009, 8, 69-85. Cover Feature.
DOI:10.1038/nrd2487
DOI:10.1038/nrd2487
6. Skepper, C.K., Dalisay, D. S., Molinski, T. F. Synthesis and antifungal activity of (-)-(Z)- dysidazirine. Organic Letters. 2008, 10, 5269-71.
DOI: 10.1021/ol802065d.
DOI: 10.1021/ol802065d.
5. Molinski, T. F., Dalisay, D. S., Morinaka, B. I., Quach, T. Configuration of natural products: Liposomal circular dichroism (LCD) for acyclic stereocenters. Planta Medica, 2008, 74, 923-924.
DOI: 10.1055/s-0028-1083949
DOI: 10.1055/s-0028-1083949
4. Thomas, T., Evans, F. F., Schleheck, D., Mai-Prochnow, A., Burke, C., Penesyan, A., Dalisay, D. S., Stelzer-Braid, S., Saunders, N., Johnson, J., Ferriera, S., Kjelleberg, S., Egan, S. Analysis of the Pseudoalteromonas tunicata genome reveals properties of a surface-associated life style in the marine environment. PLoS ONE, 2008, 3(9):e3252
DOI:10.1371/journal.pone.0003252.
DOI:10.1371/journal.pone.0003252.
3. Rogers, E. W., Dalisay, D. S., Molinski, T. F. (+)-Zwittermicin A: assignment of its complete configuration by total synthesis of the enantiomer and implication of D-serine in its biosynthesis. Angewandte Chemie International Edition Engl. 2008, 47, 8086-9.
DOI: 10.1002/anie.200801561
DOI: 10.1002/anie.200801561
2. Dalisay, D. S, Webb, J. W., Scheffel, A., Svenson, C., James, S., Holmström, C., Egan, S. and S. Kjelleberg. A mannose-sensitive haemagglutinin (MSHA)-like pilus promotes attachment of Pseudoalteromonas tunicata cells to the surface of the green alga Ulva australis. Microbiology, 2006,152, 2875-2883.
DOI: 10.1099/mic.0.29158-0
DOI: 10.1099/mic.0.29158-0
1. Mai-Prochnow, A., Evans, F., Dalisay-Saludes, D.S., Stelzer, S., Egan, S., James, S., Webb, J. S. and S. Kjelleberg. Biofilm development and cell death in the inhibitory marine bacterium Pseudoalteromonas tunicata. Applied and Environmental Microbiology, 2004, 70, 3232-8.
DOI: 10.1128/AEM.70.6.3232-3238.2004
DOI: 10.1128/AEM.70.6.3232-3238.2004